Research

A Cannabinoid Pharmacologist and Laboratory Manager since 2009, Pritesh has conducted medical cannabinoid research as it pertains to the cannabinoid receptor 2 (CB2), pharmacological testing of FDA approved drugs as potential ligands for CB2, investigated the pharmacology of cannabidiol (CBD) for CB2 and been responsible for all aspects of managing the laboratory as well as QA as it pertains to sampling, handling and testing of cannabinoid drugs.

Research Papers

CB2 cannabinoid receptor is a novel target for third-generation selective estrogen receptor modulators bazedoxifene and lasofoxifene

Publisher:
Biochemical and Biophysical Research Communications 443 (2014) 144–149
Article history:
Received 13 November 2013
Keywords:
Cannabinoid receptor
Inverse agonist
Selective estrogen receptor modulator Bazedoxifene
Lasofoxifene
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Effects of Palmitoylethanolamide on Aqueous Humor Outflow

Publisher:
Investigative Ophthalmology & amp; Visual Science, July 2012, Vol. 53, No. 8
Article History:
Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, Kentucky.
Submitted for publication December 12, 2011; revised April 15, 2012; accepted May 7, 2012
Authors:
A. Kumar; Z. Qiao,  P. Kumar,  Z.-H. Song
Corresponding Author:
Zhao-Hui Song, Department of Pharma- cology and Toxicology, University of Louisville School of Medicine, Louisville, KY
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Identification of raloxifene as a novel CB2 inverse agonist

Publisher:
Biochemical and Biophysical Research Communications 435 (2013) 76–81
Article history:
Received 30 March 2013 Available online 20 April 2013
Keywords:
Cannabinoid receptor Inverse agonist
Drug repurposing Raloxifene Osteoporosis
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Involvement of a non-CB1/CB2 cannabinoid receptor in the aqueous humor outflow-enhancing effects of abnormal-cannabidiol

Publisher:
Experimental Eye Research 100 (2012) 59e64
Article history:
Received 12 January 2012
Accepted in revised form 1 May 2012 Available online 8 May 2012
Keywords:
abnormal-cannabidiol
cannabinoid receptor
intraocular pressure
trabecular meshwork
aqueous humor outflow
p42/44 mitogen-activated protein kinase
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Structure-activity relationships of fatty acid amide ligands in activating and desensitizing G protein-coupled receptor 119

Publisher:
European Journal of Pharmacology 723 (2014) 465–472
Article history:
Received 29 March 2013 Received in revised form
18 October 2013
Accepted 23 October 2013 Available online 30 October 2013
Keywords:
G protein-coupled receptor 119
Fatty acid amides
Structure-activity relationship
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The Importance of Hydrogen Bonding and Aromatic Stacking to the Affinity and Efficacy of Cannabinoid Receptor CB2 Antagonist

Publisher:
J. Med. Chem. 2013, 56, 6593−6612
Article history:
Received: January 14, 2013
Published: July 15, 2013
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